Graphene's Unique Properties Enable Sensitive Biosensing and Biomedical Applications through its Interface with Molecules and Cells
Graphene’s interface with molecules and cells arises from its large surface area and its unique electronic and mechanical properties. Its two-dimensional structure allows for a large surface area to volume ratio, providing ample surface area for molecular interactions. Additionally, the sp2 hybridization of carbon atoms in graphene results in a unique electronic structure, which facilitates efficient electron transfer with biomolecules and cells.
This property has made graphene an ideal candidate for use in biosensors, where it can detect and monitor biomolecules such as DNA, proteins, and other molecules with high sensitivity and specificity. The large surface area of graphene provides ample space for biomolecules to attach, allowing for highly sensitive detection. Additionally, graphene’s unique electronic properties allow for efficient electron transfer between the biomolecule and the graphene surface, resulting in highly sensitive detection of even small amounts of the target molecule.
Graphene’s interface with cells has also been explored for various biomedical applications, including drug delivery, tissue engineering, and cell imaging. Its large surface area and biocompatibility make it an ideal material for use in these applications. For example, graphene-based drug delivery systems have been developed to deliver drugs directly to specific cells or tissues, while minimizing side effects. Additionally, graphene-based substrates have been used for tissue engineering, where they can provide a biocompatible and conductive surface for cell growth and differentiation.
Graphene’s ability to interface with molecules and cells is a key mechanical property that arises from its large surface area and unique electronic and mechanical properties. This property has made graphene an ideal candidate for use in a wide range of biosensing and biomedical applications, where it can detect and interact with biomolecules and cells with high sensitivity and specificity.